Anti-Neuroglobin; clone 6G1.1

Code: MABN369 D2-231

Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroglobin in human thalamus and human frontal lobe tissue.

Detect Neurog...


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€417.00 EACH
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Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroglobin in human thalamus and human frontal lobe tissue.

Detect Neuroglobin using this mouse monoclonal antibody, Anti-Neuroglobin Antibody, clone 6G1.1 validated for use in western blotting & IHC.

General description

Neuroglobin protein encoded by the gene NGB, is involved in oxygen transport in the brain. Neuroglobin is also important for neuroprotection during oxidative stress. Additionally, Neuroglobin has anti-apoptotic activity by reseting the mitochondrial membrane tigger level for cytochrome C release and the commitment to apoptosis. Neuroglobin is localized to the perikaryon, cytoplasm, and mitochondrion. Neuroglobin is predominantly expressed in the brain with strongest expression in the frontal lobe and the subthalamic nucleus and thalamus.

Immunogen

GST-tagged recombinant protein corresponding to the N-terminus of human Neuroglobin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Quality

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroglobin in 10 µg of human cortex tissue lysate.

Target description

~17 kDa observed

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcemouse
clone6G1.1, monoclonal
Gene Informationhuman ... NGB(58157)
isotypeIgG2bκ
NCBI accession no.NP_067080
Quality Level100
shipped inwet ice
species reactivityhuman
technique(s)western blot: suitable, immunohistochemistry: suitable
UniProt accession no.Q9NPG2
This product has met the following criteria to qualify for the following awards:



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